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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e4fd908c1e5648e57794d07cdea3652aca39d556d442b2b79e166d14f601b93' 
  AND token = '+wq1xEpVtz9o2etzlMSb4EAY6R6ZJZEpwiDS9+mPMVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}