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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87a8b6caaaca19c46f30c4c24901d47d0ec8727de24ae6f2a66b20d44ce14004' 
  AND token = 'UFEIebS6SezIqY383Y5JQ70E5Hrk0Tke51Ezsw4BJ24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}