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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '261e468ee6c4f31eba5bbd1ea21cb9f4133f965c7784b0b2740aa56590c16917' 
  AND token = 'TTgC2I96Wkbm0Y/50Z9Oi2WfqhqjBpbzpeDIKudHlH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}