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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c2f4fc59c0e9da065797a4d0340ebc304eb8f614daeb12ddd4d290c155b3186' 
  AND token = '81vhiKden0mx8k2sIxcX732ON8BvC7ZLyCq74TUkT0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}