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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75cdad9d861bb7c55612ab5f26cbc0a2031f88961b35c6631749e574e6d75647' 
  AND token = 'n3RPfQ2K5hH2Sm9/aUuw06EXKn3AtmFcJwgiobSUys8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}