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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e60f4ae532b030c41bb4c32361afb7e7559c47cbad3473361e200a7b9280850' 
  AND token = 'z9isyBMOB2C+PKIcE8V2BD1/NwmBKQLxmM2xwGPfpso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}