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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00ee059c025a7bc4a7853f59b6c6642a9ede2600b019ddff5941e975e9f1356f' 
  AND token = 'cJ9gKkKnPsOor+tEVxF4vHTVCEAxKdNNGCTCZM6vyTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}