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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7ff5f8a442ebb417af70dcca0fcc623267d1aabafa3b0548cf27c2456b9f43a' 
  AND token = 'sh6GnuxNY4j4IQiSoeMMdTXeN9Z0BNxFJRR7KwQiMso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}