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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0545c407f48fabbf6057b225acc6331602297d43dadfa4470923b0c6b0adf6' 
  AND token = 'BkyOoP7Y/zbVD0tnDpI3O+s4NEXes6H2bKzLTlDPOAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}