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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a7df6d1012ea2f08e002174ecda4e175d3ade4b86741e626ae3214f4042beb1' 
  AND token = 'Ppf1SRuXbJE7x3+8Q+L9eEc1nhDoRcoy8Y6uMESiemo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}