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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c720f24d029e8e65ea3017210142e75ebe06a4d1bfcd343ff1b4c1aac8c74cb5' 
  AND token = 'nYVYm0dRyIpT0ziSKiV1h89aLShi5OltrJvqzC1auxo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}