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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8651a96cd84ab8ee99fe710b95cd74022e9fa5602da7ce024e59a00a0ec275df' 
  AND token = 'ki/hkuTIrMgJ5O0khMUIeQC3GC2L9gM5dpY+mvwYZ4k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}