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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49a10486a9c1fd987c52c1829ffd49183646de74e56da4f1506cbfead3e412c9' 
  AND token = 'haVQjgG20TTftDKZgV947WcLu+1IQ8bz5z3xdNDyxno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}