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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de117c655523f64529924e841bfd089b08efa2fbd115e2b5dbc3b3fdd3b0e3fc' 
  AND token = 'UzHwQftOPCZtwMo627tiDRKsKy8P722pK7ykcRbZayg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}