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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b614e31f7154b9f9801f85f803d7a36a2a0fcb44bbdb34cb4e12f261a98d79ed' 
  AND token = 'P0dM4Y2HCpq5E9DxF/FlSY7pQbs4AG0KR3eqBoycVuI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}