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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ced437c1cea5b5b908d79f5f587efeb4062e5c27d06be7a0faa0443de5f1f5a' 
  AND token = 'fuYzlqieRxCtS8Loog9f/36MOd2XKvk88ZFntWbq6MQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}