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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af39cd5351a55b947da524f11ea97abf3ca53955e5d9526d15dd2e285041f786' 
  AND token = 'F6g2MDHIjpESptS2PZJkC8nC66s/Wv7M1bTV2HW7LxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}