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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0cb0ea5f3fc8ae75038cc1f961a13761250580aa158ea2ce87628d57d3ab547' 
  AND token = 'dZo/knXIu+PsaPv+9veeioC1/YA0/LvOzlrHpIigPhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}