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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e197b01521f1aa4880181c1c9cf43e2720551e50f9183c33e6db62284ccf9542' 
  AND token = 'AAT9/i5aJHGPGkCgdWo/RvLb0HeqpBCgvbXvx08ojr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}