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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b535dc62c7d727858d05011d8323e78b7ca3df4478a6ee7196ff08cb7ec5ebe0' 
  AND token = 'ToxI74YTNQcfOGwefO/WAL4T8sfn7DTJOiJXu9jH8b0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}