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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45eba1f498c26a7c349a68018558d25c3610c399169ff7af299ee0182bd5c60a' 
  AND token = 'kQjG1BpjqMchQa1c4Qnhzzw4MuGf1QUy1C6PtbPjoUs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}