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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d59d45db8c041968d9e82ead467fd3ca9a533ede061822bb4c8123f1f8b5814' 
  AND token = 'XgooEnxbX/itny3lY60TFVkNs1ZfODRI/uv8mUHz7Zs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}