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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cd122db2f09c23c63023246ba5e0966859444bcf9b35e7112c81eecd1d3b7d8' 
  AND token = 'XHH4RIOIK0s0NFK2XXc8PTlKU8aZTpL0H1FyeIrPn2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}