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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd881f414dd65f582836e459a9093ef4f83d7d478838ef745fe5d3c1095aa9ea6' 
  AND token = 'tUD4m0Hnb8nSLjDi3bfIT+HRWdhJ9DQILhWu7Z0d+gE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}