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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5e5d3ff00953c9b337fceffaa23aec18a4961b7d0ce0cf37c7b65ed3a11d89' 
  AND token = 'S0jN/6aZRS6YaEfmiHddrbI1hgSF112l244NhTVAyUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}