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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4500b2b10a3e1b33263fc86ef3aad6a8cacb082e80f66dcea39aa910ce77578' 
  AND token = 'aBz/aKlNwNt95Vm1x1Snkj80Z1TmmVIbVv7KVzTsqoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}