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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60e15b4ec611efe2e1907d2899fba2995777a5d051bc44fd2fddecdec3974792' 
  AND token = 'zumG5FMENPZz0AwPM+03M9yRCZwMcTucf73W5d6ZkLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}