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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '13c4835d12c63868f7746ad21f7ea23ae9f25b33db1e0079baf2312fbb3ee678' 
  AND token = 'FagYL/37HZ6hzzMe2njXd0yOphmyfnOBanlC75/HNaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}