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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '748410f0b6a1fec9b5db242bef5c02d912b1c44b6c1d8415c6e11ccf295078ce' 
  AND token = 'PN2UqUXQexwNwOXS42tLHkBDgNLfntic65Hppq0kmZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}