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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '866059b6990740c9d61a6250026f43d2105fa8789b72568c7fb4022ab9f865d3' 
  AND token = 'SfV5VStZIZ/r2S19b6EIczHAhha4/9KcF+FC2onWE3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}