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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006f08514df4ff4f6c07e00e99930b8343809f343a569a42cc8b42c34449a0da' 
  AND token = '+eiqB8VvkDb4JyoSd/DKnjJ6cHIlAEslqtJXrBUrUgU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}