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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b386ca0745ce86a81670907cee6dee5f1ab3f20c3abd3b28f8a08a6aa987279' 
  AND token = 'l52tk+5szycA07NbsDVCZm39qo/BmzAd1aS/EQbCQgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}