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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2207bfe26ea2cacc004e5eaa78979b90bc88034c2cd28934d4a1eeae9ae2dad9' 
  AND token = '3iV9plrJQQkEv//2EBJ9C5j8+pYYoOAhsEQg5xz5i8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}