SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7577184d6555512f6fc753c133c64771c597f8b250e7b148ab270ca8be12a4b' 
  AND token = '+DbbeeX6iX8apIfavPPwF69043+IwDucju9CQGj6tE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}