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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00a1c0aa29c208096ed714c0e5a75fdcaf0afa3e75397c3f5aecee3af1040413' 
  AND token = 'UhSBobHjbrcjwHljlA6NtLc3qqZ1eH6+0lLvmX/TRCk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}