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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6174621352f251e91dc81e100e71c0a1707172b1c285a50b8ea8a1c61a2fb05' 
  AND token = 'jwkc4DEEdHSS1evTd/Ke2sXBwMh7yw64CBa9o0zO4tE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}