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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28c9abd0e20ba16e2732ff4f7c3678c35a60921e64cecd4218ce7b437d39bb4e' 
  AND token = 'exODpMDUPy5TrM9LBdgcvTS4Dh4MLGlpsuy4zgnrmz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}