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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a5d0bef1be32860ee9e40b612daa67ce1451767782949ce7021a8762fb1f46d' 
  AND token = 'AFtc3T8o88AT1QIUxRqMpbdqT2qmOgDo29GWVIU7nHc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}