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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61cdfd1bdf55b6750dc7df6e70a9a31120d210f47c8e137205b93727b2118625' 
  AND token = 'oLs6V4axdFL9VgxI8kQ3JugCkKsfsQjxgSOMT4us9bA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}