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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3304601acf394a286ed730439526d691a88b66c5628175a82e98387811929760' 
  AND token = 'i5fVbVa72jD1opurT/5pEPpL5SQ3T0DBBHCCgqGh2ig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}