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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46b43bf4b40183bddcaf2699a0455e8b390a78b0cf249ff4059d7c0c01cb5cd' 
  AND token = 'VuYlbwtg0Pn+3FaV8m2C+LZ3DlPmZx+l5/4wPyafj/Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}