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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '640d1efd17a3f650c69da08428ba0e620d350d591232dc2b6ce0665860ed8233' 
  AND token = 'tejeROB9BEvFSosRdpbOevFj8/+pk7dM9pUcv8EpAwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}