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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d7d0eec96b25248633e5725302cf922fc74401dec86f5bb4ad4c56629573ec5' 
  AND token = 'r0rSkMvthKkauwuXlxccCsvJUHhavgYdy3uwbW4OTEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}