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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f788abb38ff6a1c85798dee6c136c9165e6faaa3f4d668ea29066d22aeb3666d' 
  AND token = 'SI2bZ6/QFBm0m6HcKDwFmsioEOf4PHlnU4KkCZI0u48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}