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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '328f2894cdab9762fbc96a959a3d3810f495e54bbb648d4a9452a2b1ef2f2652' 
  AND token = 'DShd+RUWHj639QCr/0fN9okiAXq8/Dc2b0QIQsWfKnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}