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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c86219e3437ee160caa11bc105fe143512303313e730b58a8253b49dbdee6210' 
  AND token = 'r4N5l/i12TZ8OrW1FNePaXi5wqwQeAbmDjhlTwiFrME=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}