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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd52afdd435865b250299479bb6f11b6a5ea1247acc65e270064c4ac78f62003d' 
  AND token = 'dG4FPHei57q4h2sBVrqQ3UrArua8YGbm0FbvOGFjjIY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}