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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e13f16735e9b753f628df0c0c885dfe29be3fa8a3e30d02494608ee88a7e684a' 
  AND token = 'TAFaPSKWbIceo++QzO13GUedEbm1f+xk31TsFTgxbIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}