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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '384136f4b6f37bf2bf0ad70fe5588177eea14e05f20585fc27cadcf7a4227db5' 
  AND token = 'YiHVOzUMVzNRgKWriY5zCCPrNOHPtBlcK8h9Pvb0sQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}