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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '372ebcb6f2e23d10063e84b7bd0fb66d8da384980e3fda6748640762587890f1' 
  AND token = 'wdWRSIpUEm0GqY39VXOSsuo9zoBpdt+BrjIOjghk8fI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}